- Growth Retardation.
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Duk Hi Kim
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J Korean Endocr Soc. 1996;11(4):369-376. Published online November 7, 2019
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 Abstract
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- No abstract available.
- Clinical Effects of E. coli Derived Recombinant Human Growth Hormone (DA - 3001) in Patients with Growth Hormone Deficiency.
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Sei Won Yang, Jeh Hoon Shin, Duk Hi Kim, Byung Churl Lee, Hyung Ro Moon
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J Korean Endocr Soc. 1995;10(4):377-385. Published online November 7, 2019
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Abstract
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- Recently, methionyl-hGH was produced in the E. coil K-12, W3110 by recombinant DNA technology in Korea. In this paper, the clinical efficacy and immunogenicity of this GH were studied in 43 patients with growth hormone deficency.The subjects of this study were aged 4.3-18.5 years and each patient received GH 0.5-0.71U/kg week subcutaneously, 6-7 times a week for 1 year. During treatment, height, body weight and bone age were checked. Blood count, urinalysis, blood chemistry and thyroid hormonal concentrations were checked before and every 3 months. The measurement of IGF-1 was performed and assay of antibody against hGH was performed before and every 6 months.The height velocities significantly increased from 3.7+-3.0 cm/year to 11.0+-4.2 cm/year and 9.9+-3.2 cm/year at 6 and 12 months after GH therapy, respectively. The Height SDS were significantly improved after GH therapy with increasing ratio of bone age to chronological age from 0.60+-0.19 at pretreatment to 0.68+-0.16 at 6 month, 0.69+-0.16 at 12 month of therapy. The plasma IGF-1 levels significantly increased during treatment. Three out of 35 patients(8.3%) showed antibody against hGH after 1 year of treatment. Thoughout study, we could not observe any remarkable side effect with GH treatment.These results indicate that this E. coli derived methionyl recombinant growth hormone is effective in improving the index of linear growth in the children with growth hormone deficiency without significant side effect.
- Clinical usefulness of urinary growth hormone measurements in adults.
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Yoon Sok Chung, Hyun Chul Lee, Kap Bum Huh, Duk Hi Kim, Myung Hee Lee
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J Korean Endocr Soc. 1993;8(4):398-403. Published online January 1, 2001
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Abstract
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- No abstract available.
- Clinical effects of eutropin(LBD-003) in patients with growth hormone deficiency.
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Duk Hi Kim
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J Korean Endocr Soc. 1992;7(4):343-351. Published online January 1, 2001
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Abstract
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- No abstract available.
- Thyrotropin secreating pituitary adenoma.
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Eun Jig Lee, Kyung Rae Kim, Hyeon Man Kim, Yoon Sok Chung, Kwang Jin Ahn, Kyung Mi Lee, Sung Kil Lim, Hyun Chul Lee, Duk Hi Kim, Dong Ik Kim, Doe Heum Yoon, Yong Gu Park
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J Korean Endocr Soc. 1992;7(4):331-342. Published online January 1, 2001
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Abstract
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- No abstract available.
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